Cannabinoids are powerful, but this guide reveals the secrets to their transformative effects.
Cannabinoids are powerful compounds. Were it not for them, there would be no cannabis boom.
These compounds are produced in little hairs surrounding a cannabis flower. When you consume cannabis, you’re only interested in consuming these hairs – or at least what they contain. Neither the flower, nor the leaves, nor stalk, nor stem contains anything of interest as far as the benefits of cannabis go.
And, while cannabinoids like tetrahydrocannabinol (THC) and cannabidiol (CBD) get a lot of attention, they wouldn’t have nearly as strong an effect on the human body without the support from other compounds.
These helpers include the possibly 100-plus other cannabinoids produced by the cannabis plant, as well as constituents of another class of compounds altogether.
These other molecules are called terpenes. They all work together to help THC get you even higher, or boost CBD’s ability to relieve anxiety.
Cannabinoids and terpenes working together create what’s called an entourage effect. Because it can be a little complicated, I wanted to take out some of the science jargon – so I had my team put together this guide on the subject.
We’ve been talking more about the science of cannabis lately because there are some pharmaceutical investments out there that we’ve been watching.
Blasting Open the Bodies Gates
And, as we are becoming increasingly aware, these compounds can provide useful services within the human body as well.
Here are a couple of examples of how terpenes work with cannabinoids to improve their overall effect on your body.
The most abundant terpene in cannabis is β-myrcene. You can also find it in hops and mango. And when you see its effect on cells, you start to see how THC and CBD work better when β-myrcene comes along for a ride.
β-myrcene also allows more things to pass through tissue. In fact, it is used in CBD and THC topical patches to increase the absorption of these cannabinoids through the skin and into the bloodstream. It’s so effective at letting substances pass that it also lowers the resistance of the blood-brain barrier. This increased permeation means that cannabinoids and other terpenes can more effectively cross into the brain, as well as letting more β-myrcene through.
Another function β-myrcene performs in the body is to inhibit the action of metabolic pathways responsible for inflammation. It is this action that contributes to its anti-inflammatory properties. This reduced inflammation also reduces pain over time.
CBD also reduces inflammation. So, not only does β-myrcene attack the same symptom, it opens channels to let more of itself and CBD through, boosting the healing effects above the results of a similar dose of CBD isolate.
β-myrcene also has a similar effect boosting THC’s power when it accompanies THC into your brain.
THC gets you high by interacting with what’s called the CB1 receptor. These are found only in the central nervous system, which includes the brain.
It’s that interaction that gets you high.
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Yet another property of β-myrcene is to improve how well the CB1 receptor absorbs THC. Thus, between this terpene allowing more THC to enter the brain, boosting how much TCH gets taken in by the CB1 receptor, and having a sedative effect, THC and β-myrcene work together to make you so relaxed that you can’t leave your couch – aka, couch lock.
And now that you know what the entourage effect is all about, let’s talk about how it is going to make you money.
Canopy Growth Purchases Leading Research Company
Cannabis and the entourage effect are core to the marketing of CBD health and wellness companies.
Back in November 2018, Canopy Growth Corp. (NYSE: CGC) purchased cannabis research company ebbu LLC.
Scientists at ebbu develop proprietary formulations of cannabinoids and terpenes, and these formulations create precise experiences or sensations.
To better understand the process, the team at ebbu breaks down the varying and inconsistent strains of cannabis into these compounds. The formulations are reportedly more consistent than just plant matter alone.
Consistency solves a problem because there is still a lot of inconsistency out there, particularly in the black market, and the cannabis industry needs to move away from that inconsistency.
When you go to Starbucks, you know that your caramel macchiato is going to taste the same in Las Vegas as it would in Nashville.
With a cannabis product, consumers are starting to expect and demand a consistent experience and want a product to perform as advertised.
In the image above, you can see that, when finding out how the compounds all work together, the ebbu team can create a tailored experience.
And, ultimately, the cannabis companies that figure out how to deliver a consistent product will claim the biggest share of the fastest growing market investors will see for a generation.
Executive Director, National Institute for Cannabis Investors
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6 responses to “Marijuana Improves with Help from Friends”
August 02 2019